ChemIDplus A TOXNET DATABASE

Substance Name: Arsenic
RN: 7440-38-2
InChIKey: RQNWIZPPADIBDY-UHFFFAOYSA-N

Note

  • A shiny gray element with atomic symbol As, atomic number 33, and atomic weight 75. It occurs throughout the universe, mostly in the form of metallic arsenides. Most forms are toxic. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), arsenic and certain arsenic compounds have been listed as known carcinogens. (From Merck Index, 11th ed)

Molecular Formula

  • As

Molecular Weight

  • 74.922
 

Classification Codes

Classification Codes

  • Drug / Therapeutic Agent
  • Human Data
  • Mutation data
  • Reproductive Effect
  • Tumor data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 1
  • 2011 CERCLA Priority List, Rank: 1
  • Known to be a carcinogen
  • Overall Carcinogenic Evaluation: Group 1
  • Reportable Quantity (RQ) = 1 lb
  • TWA see 1910.1018 for inorganic compounds as As; 0.5 mg/m3 for organic compounds as As
  • TWA:0.01 mg/m3; Confirmed human carcinogen; BEI

Names and Synonyms

Name of Substance

  • Arsenic

MeSH Heading

  • Arsenic

Synonyms

  • Arsen
  • Arsen [German,Polish]
  • Arsenic
  • Arsenic Black
  • Arsenic-75
  • Arsenicals
  • Arsenicum album
  • CCRIS 55
  • Colloidal arsenic
  • EINECS 231-148-6
  • Gray arsenic
  • Grey arsenic
  • HSDB 509
  • Metallic arsenic
  • UNII-N712M78A8G

Systematic Names

  • Arsenic
  • Arsenic compounds

Superlist Names

  • Arsenic
  • Arsenic and arsenic compounds
  • Arsenic and certain arsenic compounds
  • Arsenic [UN1558] [Poison]
  • Arsenic, elemental
  • Arsenic, inorganic
  • Arsenic, organic compounds
  • Arsenic, water-soluble compounds, n.o.s.
  • UN1558

Registry Numbers

CAS Registry Number

  • 7440-38-2

Other Registry Numbers

  • 39277-51-5
  • 55624-62-9

System Generated Number

  • 0007440382

Structure Descriptors

InChI

1S/As

InChIKey

RQNWIZPPADIBDY-UHFFFAOYSA-N

Smiles

[As]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child TDLo oral 4mg/kg (4mg/kg) CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE

BLOOD: CHANGES IN LEUCOCYTE (WBC) COUNT
Pediatric Emergency Care. Vol. 13, Pg. 394, 1997.
Link to PubMed
guinea pig LDLo intraperitoneal 10mg/kg (10mg/kg) LIVER: FATTY LIVER DEGERATION

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 81, Pg. 164, 1918.
guinea pig LDLo subcutaneous 300mg/kg (300mg/kg)   Archivio di Science Biologiche Vol. 24, Pg. 442, 1938.
man TDLo oral 7857mg/kg/55Y (7857mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"

GASTROINTESTINAL: CHANGE IN STRUCTURE OR FUNCTION OF ESOPHAGUS

BLOOD: HEMORRHAGE
Canadian Medical Association Journal. Vol. 120, Pg. 168, 1979.
Link to PubMed
mouse LD50 intraperitoneal 46200ug/kg (46.2mg/kg) BEHAVIORAL: ATAXIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
mouse LD50 oral 145mg/kg (145mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.
rabbit LDLo subcutaneous 300mg/kg (300mg/kg)   Archivio di Science Biologiche Vol. 24, Pg. 442, 1938.
rat LD50 intraperitoneal 13390ug/kg (13.39mg/kg)   Toxicology. Vol. 64, Pg. 191, 1990.
Link to PubMed
rat LD50 oral 763mg/kg (763mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(12), Pg. 53, 1987.