ChemIDplus A TOXNET DATABASE

Substance Name: 12-Hydroxy-5,8,10,14-eicosatetraenoic acid
RN: 59985-28-3
InChIKey: ZNHVWPKMFKADKW-GIZKKEBHSA-N

Note

  • A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274(3):1545-51; J Natl Cancer Inst 1994; 86(15):1145-51)

Molecular Formula

  • C20-H32-O3

Molecular Weight

  • 320.47
 

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • 12-Hydroxy-5,8,10,14-eicosatetraenoic acid

MeSH Heading

  • 12-Hydroxy-5,8,10,14-eicosatetraenoic acid

Synonyms

  • 12-Hete
  • 12-Hydroxy-5,8,10,14-eicosatetraenoic acid
  • 12-R-Hete
  • 12-S-Hete
  • 12-S-Hydroxyeicosatetraenoic acid

Systematic Name

  • 5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-

Registry Numbers

CAS Registry Number

  • 59985-28-3

System Generated Number

  • 0059985283

Structure Descriptors

InChI

1S/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7+,11-8+,13-10+,17-14+

InChIKey

ZNHVWPKMFKADKW-GIZKKEBHSA-N

Smiles

C(\[C@@H](C\C=C\CCCCC)O)=C\C=C\C\C=C\CCCC(O)=O