Substance Name: Oxandrolone [USAN:USP:INN:BAN:JAN]
RN: 53-39-4
InChIKey: QSLJIVKCVHQPLV-PEMPUTJUSA-N

Note

  • A synthetic hormone with anabolic and androgenic properties.

Molecular Formula

  • C19-H30-O3

Molecular Weight

  • 306.443
2D chemical structure of 53-39-4
 

Classification Codes

Classification Codes

  • Anabolic Agents
  • Androgen
  • Androgens
  • Hormone
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Reproductive Effect

Superlist Classification Code

  • DEA Schedule III

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Oxandrolone
  • Oxandrolone [USAN:USP:INN:BAN:JAN]

MeSH Heading

  • Oxandrolone

Synonyms

  • 17beta-Hydroxy-17-methyl-2-oxa-5alpha-androstan-3-one
  • 2-Oxa-5alpha-androstan-3-one, 17beta-hydroxy-17-methyl-
  • 2-Oxaandrostan-3-one, 17-hydroxy-17-methyl-, (5alpha,17beta)-
  • 8075 C. B.
  • 8075 C.B.
  • 8075 CB
  • Anavar
  • Dodecahydro-3-hydroxy-6-(hydroxy-methyl)-3,3a,6-trimethyl-1H-benz(e)indene-7-acetic acid delta-lactone
  • EINECS 200-172-9
  • HSDB 3373
  • Lonavar
  • NSC 67068
  • Ossandrolone
  • Ossandrolone [DCIT]
  • Oxandrin
  • Oxandrolona
  • Oxandrolona [INN-Spanish]
  • Oxandrolone
  • Oxandrolonum
  • Oxandrolonum [INN-Latin]
  • Protivar
  • Provitar
  • SC 11585
  • UNII-7H6TM3CT4L
  • Vasorome

Systematic Names

  • 17-beta-hydroxy-17-methyl-2-oxa-androstan-3-one (9CI)
  • 2-Oxa-5-alpha-androstan-3-one, 17-beta-hydroxy-17-methyl-
  • 2-Oxa-5alpha-androstan-3-one, 17beta-hydroxy-17-methyl- (8CI)
  • 2-Oxaandrostan-3-one, 17-hydroxy-17-methyl-, (5-alpha,17-beta)- (9CI)
  • 2-Oxaandrostan-3-one, 17-hydroxy-17-methyl-, (5alpha,17beta)-
  • Oxandrolone

Superlist Names

  • 17alpha-Methyl-17beta-hydroxy-2-oxa-5alpha-androstan-3-one
  • DEA No. 4000
  • Oxandrolone

Registry Numbers

CAS Registry Number

  • 53-39-4

System Generated Number

  • 0000053394

Structure Descriptors

InChI

1S/C19H30O3/c1-17-11-22-16(20)10-12(17)4-5-13-14(17)6-8-18(2)15(13)7-9-19(18,3)21/h12-15,21H,4-11H2,1-3H3/t12-,13+,14-,15-,17-,18-,19-/m0/s1

InChIKey

QSLJIVKCVHQPLV-PEMPUTJUSA-N

Smiles

C1[C@@H]2[C@@H]([C@@]3([C@@H](CC(=O)OC3)C1)C)CC[C@@]1([C@H]2CC[C@]1(C)O)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo oral 2400ug/kg/2W- (2.4mg/kg) BEHAVIORAL: EUPHORIA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: IRRITABILITY
Journal of Clinical Psychiatry. Vol. 46, Pg. 354, 1985.
mouse LD50 intraperitoneal 922mg/kg (922mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 418, 1969.
Link to PubMed
mouse LD50 oral 1832mg/kg (1832mg/kg) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 418, 1969.
Link to PubMed
mouse LD50 subcutaneous > 11gm/kg (11000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 418, 1969.
Link to PubMed
rabbit LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. 6, Pg. 149, 1982.
rat LD50 intraperitoneal 4893mg/kg (4893mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 418, 1969.
Link to PubMed
rat LD50 oral > 10gm/kg (10000mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 418, 1969.
Link to PubMed
rat LD50 subcutaneous > 10gm/kg (10000mg/kg)   Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 65, Pg. 418, 1969.
Link to PubMed

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 236.5 deg C   EXP
log P (octanol-water) 2.580 (none)   EST
Atmospheric OH Rate Constant 2.57E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by Syracuse Research Corporation.
See all available property data for this compound, including references.