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Substance Name: Methoprene [INN]
RN: 40596-69-8
InChIKey: NFGXHKASABOEEW-LDRANXPESA-N

Note

  • Juvenile hormone analog and insect growth regulator used to control insects by disrupting metamorphosis. Has been effective in controlling mosquito larvae.

Classification Codes

  • Agricultural Chemical
  • Growth regulator / Fertilizer
  • Mutation data

Molecular Formula

  • C19-H34-O3

Molecular Weight

  • 310.475
 

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Names and Synonyms

Name of Substance

  • Juvemon
  • Methoprene
  • Methoprene (unspecified)
  • Methoprene [ANSI:BSI:ISO]
  • Methoprene [INN]

MeSH Heading

  • Methoprene

Synonyms

  • (E,E)-1-Methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • (E,E)-Isopropyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • Altosid
  • Altosid IGR
  • Altosid Liquid Larvicide
  • Altosid SR 10
  • Apex
  • Apex (pesticide)
  • Bioprene BM Fire Ant Killer Bait
  • Caswell No. 028AAA
  • Diacon
  • Dianex
  • dl-Isopropyl 11-methoxy-3,7,11-trimethyl-trans-2,4-dodecadienoate
  • EINECS 254-993-2
  • ENT 70460
  • EPA Pesticide Chemical Code 105401
  • HSDB 6926
  • Isopropyl (EE)-(RS)-11-Methoxy-3,7,11-trimethyldodeca-2,4-dienoate
  • Isopropyl(2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • Juvemon
  • Kabat
  • Manta
  • Manta (hormone)
  • Methoprene
  • Methoprene S
  • Methoprenum
  • Methoprenum [INN-Latin]
  • Metopreno
  • Metopreno [INN-Spanish]
  • Minex
  • OMS 1697
  • Pharoid
  • Precor
  • Starbar Inhibitor
  • UNII-8B830OJ2UX
  • Yuvemon
  • ZPA 1019
  • ZR 515

Systematic Names

  • 2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, 1-methylethyl ester, (2E,4E)-
  • 2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, 1-methylethyl ester, (E,E)-
  • Isopropyl (2E,4E)-(7S)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • Isopropyl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate

Superlist Name

  • Methoprene

Registry Numbers

CAS Registry Number

  • 40596-69-8

Other Registry Number

  • 41205-06-5

System Generated Number

  • 0040596698

Structure Descriptors

InChI

1S/C19H34O3/c1-15(2)22-18(20)14-17(4)11-8-10-16(3)12-9-13-19(5,6)21-7/h8,11,14-16H,9-10,12-13H2,1-7H3/b11-8+,17-14+

InChIKey

NFGXHKASABOEEW-LDRANXPESA-N

Smiles

C(CCC[C@@H](C\C=C\C(=C\C(OC(C)C)=O)C)C)(OC)(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 5gm/kg (5000mg/kg)   EHP, Environmental Health Perspectives. Vol. 14, Pg. 119, 1976.
Link to PubMed
guinea pig LC50 inhalation > 210gm/m3 (210000mg/m3)   EHP, Environmental Health Perspectives. Vol. 14, Pg. 119, 1976.
Link to PubMed
rabbit LD50 oral 3038mg/kg (3038mg/kg)   "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc of Chemistry, 1983-86Vol. A615, Pg. 1986,
rabbit LD50 skin 3gm/kg (3000mg/kg)   EHP, Environmental Health Perspectives. Vol. 14, Pg. 119, 1976.
Link to PubMed
rat LC50 inhalation > 210gm/m3 (210000mg/m3)   EHP, Environmental Health Perspectives. Vol. 14, Pg. 119, 1976.
Link to PubMed
rat LD50 oral 25gm/kg (25000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 56(10), Pg. 72, 1991.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point < 25 deg C   EXP
log P (octanol-water) 5.5 (none)   EXP
Water Solubility 1.4 mg/L   EXP
Vapor Pressure 2.36E-05 mm Hg 25 EXP
Henry's Law Constant 6.89E-06 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 8.30E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by Syracuse Research Corporation.
See all available property data for this compound, including references.